Abstract: This study addresses the asymmetric large deformation of the roof and two sides in the 9106 working face return airway of Wangzhuang Coal Mine, particularly the more severe roof deformation near the solid coal side.Through comprehensive analysis, it was determined that the primary cause is the combined effect of mining activities and monorail crane operations, with cyclic loads from the monorail crane exacerbating damage to the solid coal side.Numerical simulation was employed to investigate the influence of monorail crane positioning and anchoring depth on roadway deformation.The results indicate that positioning the monorail crane approximately 2.5 m from the solid coal side with an anchoring depth of 13 m can effectively suppress asymmetric deformation.A “bolt-cable+grouting” control strategy was developed and implemented, successfully reducing maximum roadway deformation from 1.5 m to below 0.3 m, and effectively controlling the asymmetric large deformation.