Abstract: In view of the centralized on-line operation of the current intelligent system equipment, there is a disconnect between the use of equipment and operation and maintenance, resulting in insufficient sustainable production efficiency of the mine, and a huge operation and maintenance task of the mine equipment.A digital twin mine operation and maintenance system based on mixed reality technology is proposed and developed.Based on the mine system big data service combined with the adaptive collection service of the underlying industrial protocol hardware equipment, and the integration, analysis and storage capabilities of data, the intelligent data analysis of big data and the fault prediction of intelligent equipment are carried out through the operation and maintenance service scheduling platform.The combination of digital twin and MR Mixed reality technology, through the combination of virtual and reality human-machine interaction behavior, to achieve the status monitoring of working surface equipment, fault troubleshooting and maintenance, staff virtual training and learning goals, effectively reduce operation and maintenance costs, improve production efficiency.The application results show that MR Mixed reality intelligent operation and maintenance system can quickly and intelligently complete operation and maintenance tasks, improve the professional skill level of operation and maintenance personnel, and significantly improve the production process and efficiency, effectively realizing the goal of “cost reduction, security and efficiency increase” of intelligent mine.