Abstract: The construction of Panjiayao Mine is of great significance for promoting the construction of national energy bases and ensuring national energy security.With the increasing depth of coal seam mining in China and the increasingly complex geological environment conditions, the threat of water damage to coal seam roof is becoming increasingly prominent.Based on the hydrogeological exploration results of Panjiayao Mine, we focus on studying the risk assessment method of water inrush from the floor of the fault structure development zone in Panjiayao Mine No.5 coal seam.Combined with relevant regulations and standards, multiple methods such as water inrush coefficient method and safety waterproof layer thickness calculation method are used to comprehensively evaluate the water inrush risk of Ordovician carbonate rock fissure karst water pressure mining, and the water inrush risk of Ordovician carbonate rock fissure karst water pressure mining is comprehensively evaluated.These evaluation results provide important basis for developing targeted measures to prevent water inrush from confined water, and accumulate rich experience for water prevention and control work in working faces under similar hydrogeological conditions.