Abstract: The 14# coal seam of Queshan Coal Mine in Datong, Shanxi Province has the characteristic of easy spontaneous combustion, which is difficult to be predicted by conventional methods.Laboratory tests were carried out on coal samples from the mine to analyze the relationship between different indicator gases in the spontaneous combustion process of coal.The data of CO,CO₂,CH₄,C₂H₆,C₂H₄,C₃H₈,C₃H₆ and C₂H₂ gases at different coal temperatures were measured in the laboratory to explore the relationship between each indicator gas and coal temperature.The results of the study show that the concentration of CO,C₂H₆,C₂H₄,C₃H₈,C₃H₆ and C₂H₂ has the optimum variation rule with temperature.If the 14# coal seam contains the aforementioned gases, there is an oxidative warming phenomenon in the coal, so it is suggested that the 14# coal seam should use CO,C₂H₄ and C₂H₂ as the main and C₂H₆,C₃H₈ and C₃H₆ as the auxiliary gases as the natural ignition marker gases of the seam, so as to master the spontaneous combustion of the coal.Finally, it was verified through actual engineering that CO can be used as an indicator gas for predicting the natural ignition of coal, and its emergence temperature is around 38 ℃,and its predicted temperature range is before 95 ℃.